Rapid Relief for Treatment-Resistant Conditions

IV Ketamine Infusion Therapy

When standard treatments fall short, IV Ketamine offers a powerful, rapid-acting path to relief. Administered in our calming, supportive clinical environment, this proven therapy helps patients break free from severe depression and anxiety to finally reclaim their lives.

Accepting Most Major Insurances

Relief For When Other Treatments Fail

Ketamine therapy can be helpful even when other pharmaceuticals have failed. Ketamine is generally safe, well tolerated and can be life-changing for those who respond to it.

Several scientific studies, including those conducted at Yale University and the National Institute of Mental Health, have shown that low dose intravenously administered ketamine can dramatically improve symptoms associated with depression and many anxiety disorders. Often, even when other treatments have failed to provide any relief, IV ketamine is effective.

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Finding Relief For

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The Treatment Protocol & Our Team Approach

All new patients have a series of six infusions spaced over two or three weeks. Each infusion is typically 40-60 minutes long, painless, and well tolerated. Most patients experience significant relief during the series and many remain symptom-free for extended periods of time following the initial treatment protocol.

At Kansas Mental Health Medicine we take a team approach in administering and monitoring your treatments which we believe also enhances your therapeutic team!

Your Ketamine Care Team

At Kansas Mental Health Medicine, we take a collaborative team approach to administering and monitoring your IV ketamine treatments. Dr. Trever Krehbiel and our experienced staff are dedicated to providing an exceptional level of support, ensuring your infusions are safe, comfortable, and tailored to your unique needs.

Common Questions About Ketamine Therapy

It is important to understand the details of your care before beginning a new treatment protocol. From expected outcomes and side effects to insurance coverage and aftercare, here is everything you need to know about receiving IV ketamine at Kansas Mental Health Medicine.

Will my insurance company pay for ketamine therapy?2026-03-25T11:02:56-05:00

No. Because IV ketamine therapy for mood and anxiety disorders is off-label, insurance companies do not provide reimbursement. Thankfully, IV ketamine therapy is not only the most effective treatment, it is also the least expensive.

Do I need to stop taking any of my current medications before I begin ketamine therapy?2026-03-25T11:02:42-05:00

No. You should not make any adjustments in your current medications without specific approval from the prescriber. It is important to note that while there is some speculation related to benzodiazepine and lamotrigine and their effect on ketamine infusions, there is no actual evidence to support adjustments in either in advance of therapy. While these medications may reduce the dissociative effects of ketamine during an infusion, our experience suggests that they have no negative impact on outcomes.

What should I expect during ketamine therapy?2026-03-25T11:02:27-05:00

Ketamine is administered over a period of 40 minutes. The dose is determined by your weight. The amount of ketamine administered is not enough to cause a loss of consciousness, so you will remain awake. During the infusion, some patients experience a waking dream-like state or mild euphoria. Most find the treatment very pleasant. Patient generally leave the office within a few minutes following the infusion and feel quite normal. It is important not to drive, operate any dangerous machinery, or make any important decisions until the day after a ketamine infusion, as reaction times can be significantly diminished immediately following the infusion.

Are ketamine infusions addictive?2026-03-25T11:26:34-05:00

No. The dosage and frequency of infusions are such that addiction is not possible. In contrast, patients using oral or nasal ketamine often develop a tolerance, addiction, and side effects.

What medical conditions could keep me from receiving ketamine?2026-03-25T11:01:59-05:00

There are very few. Dr. Krehbiel will discuss contraindications with you before you receive your first infusion.

Are there any long-term side effects with ketamine therapy?2026-03-25T11:01:47-05:00

IV Ketamine therapy following the NIMH protocol results in no known long-term side effects.

If ketamine therapy works for me how soon will I begin to feel better?2026-03-25T11:01:35-05:00

A very small percentage of patients begin to feel better within hours of the first infusion. Patients with thoughts of self-harm often notice those thoughts dissipating first with a dramatic relief of dread and hopelessness. Many patients do not notice a significant mood improvement until they’ve had several infusions. Almost all patients who will respond feel measurably better after the series of six infusions.

Will I require ketamine infusions for the rest of my life?2026-03-25T11:01:23-05:00

Some patients seem to achieve long-term relief after the initial series of six infusions and others require additional infusions at varying frequencies to maintain relief. Aftercare is an important part of ketamine therapy and Dr. Krehbiel will work with you to determine the best approach for you to achieve lasting relief.

How many ketamine infusions will I receive?2026-03-25T11:01:03-05:00

Initially, all patients receive a series of six infusions spaced over two or three weeks. This follows the protocol developed during the NIMH trial and is the best predictor of efficacy.

Where is the treatment performed?2026-03-25T11:00:53-05:00

All treatments are performed, on an outpatient basis, in Dr. Krehbiel’s relaxing and comfortable treatment room.

Do I need a referral to begin therapy?2026-03-25T11:00:35-05:00

No. If you are not currently a patient of Dr. Trever Krehbiel’s, he will meet with you to discuss your diagnosis prior to beginning treatment. Patients who are already seeing Dr. Krehbiel will work with him to determine readiness during a pre-infusion consultation.

Will ketamine therapy help my treatment resistant depression?2026-03-25T11:00:18-05:00

Based on a landmark study conducted by the National Institute of Mental Health, up to 70% of all patients can expect significant relief after a series of six ketamine infusions. We have found that by curating the patient experience, providing an exceptional level of support, and setting realistic expectations, we consistently see outcome metrics that outperform the NIMH study. It is important to understand that it is impossible to predict an outcome for a specific patient. Thankfully, owing to the ease and accessibility of treatment and the absence of known side-effects, it is possible to explore the benefits of therapy without risk.

Ready to explore if IV Ketamine is right for you?